孤菲肽/痛敏肽抗体
规格：1mg/1ml
英文名： Nociceptin
别名： PNOC; N/OFQ; N23K; N23K/N27K; Nociceptin, included; Npnc1; OFQ; OFQ/N; Orphanin FQ; PPNOC; prepronociceptin; Propronociceptin; PNOC_HUMAN.
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Nocicept
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
孤菲肽/痛敏肽抗体细胞定位：分泌型蛋白
产品介绍：background: Nociceptin (PNOC) is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. Expressed predominantly in the spinal cord and brain, being more abundant in the hypothalamus and striatum. Also found in small amounts in ovary. Belongs to the opioid neuropeptide precursor family. Function: Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development (By similarity). Subcellular Location: 孤菲肽/痛敏肽抗体Secreted. Tissue Specificity: Predominantly in the brain and spinal cord. Similarity: Belongs to the opioid neuropeptide precursor family. Gene ID: 5368 Database links: Entrez Gene: 5368 Human Entrez Gene: 18155 Mouse Entrez Gene: 25516 Rat Omim: 601459 Human SwissProt: Q13519 Human SwissProt: Q64387 Mouse SwissProt: Q62923 Rat Unigene: 88218 Human Unigene: 16347 Mouse Unigene:孤菲肽/痛敏肽抗体486163 Mouse Unigene: 87935 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 孤菲肽（Nociceptin又称为Orphanin FQ; PPNOC; ORL1）是新发现的一种神经肽，由17个氨基酸组成，又称痛敏肽。消化道肿瘤病人的血浆中OFQ含量明显高于对照组，尤以结肠癌、胃癌*为明显。
孤菲肽/痛敏肽抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid