血管活性肠肽抗体
规格：1mg/1ml
英文名： VIP
别名： Vasoactive Intestinal peptide; MGC13587; Peptide histidine methioninamide 27; PHM 27; PHM27; PHV42; VIP peptides precursor; PHI; Peptide Histidine Isoleucine; Vasoactive intestinal peptide; VIP_HUMAN.
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VIP
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
血管活性肠肽抗体细胞定位：分泌型蛋白
产品介绍：background: Growth Factor and Hormones VIP(Vasoactive Intestinal peptide) is a 28-amino acid peptide structurally related tosecretin. It was originally isolated from intestinal extracts and shown to be a potent vasodilator. Subsequent work demonstrated that VIP is very widely distributed in the peripheral and central nervous systems, and probably should not be considered a true GI hormone. A huge number of biological effects have been attributed to VIP. With respect to the digestive system, VIP seems to induce smooth muscle relaxation (lower esophageal sphincter, stomach, gallbladder), stimulate secretion of water into pancreatic juice and bile, and cause inhibition of gastric acid secretion and absorption from the intestinal lumen. Function: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility血管活性肠肽抗体, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. PHM and PHV also cause vasodilation. Subcellular Location: Secreted. Similarity: Belongs to the glucagon family. Gene ID: 7432 Database links: Entrez Gene: 7432 Human Entrez Gene: 22353 Mouse Entrez Gene: 117064 Rat Omim: 192320 Human SwissProt: P01282 Human SwissProt: P32648 Mouse SwissProt: P01283 Rat Unigene: 53973 Human Unigene: 98916 Mouse Unigene: 18675 Rat Important Note: This product as supplied is intended for research use only, not for use i血管活性肠肽抗体n human, therapeutic or diagnostic applications. VIP是一个广泛分布于**神经系统和周围神经系统的神经肽，他有较强的血管舒张作用、支气管扩张作用、平滑肌松弛作用，具有很多**系统细胞的活性，是一个促分裂剂。 近年来研究表明，VIP也是一种生长因子,它对多种恶性肿瘤的发生、发展、增殖和分化起重要的促进作用，血管活性肠肽的神经保护作用受到来自胶质细胞的活性依赖的神经营养因子释放的调节。VIP和PACAP有很高的同源性。
血管活性肠肽抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 **学 神经生物学 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid