分泌素受体抗体
规格：1mg/1ml
英文名： Secretin receptor
别名： 6530402O03Rik, MGC102218, MGC93381, SCTR, SR; Secretin receptor; SCT-R; SCTR_HUMAN.
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from the middle of
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
分泌素受体抗体细胞定位：细胞膜
产品介绍：background: The receptor for secretin is a class 2 (or class B) G protein coupled receptor that signals through Gs to stimulate cAMP production. Along with its traditional role in the pancreas, studies in secretin-deficient mice have shown miscommunication between the CA3 Schaffer collateral and CA1 pyramidal neurons, causing a deficiency in synaptic transmission. This miscommunication of CA1 dendrites is found in Autism, Rett Syndrome, and most forms of mental retardation, suggesting secretin could be a potential target for treatment of these disorders.分泌素受体抗体 Function: This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 2 family. Gene ID: 6344 Database links: Entrez Gene: 6344 Human Omim: 182098 Human SwissProt: P47872 Human Unigene: 42091 Human Important Note: 分泌素受体抗体This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
分泌素受体抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 生长因子和** 细胞膜受体 ***病 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid