神经生长因子4/5抗体
规格：1mg/1ml
英文名： Neurotrophin 4
别名： GLC1O; Neurotrophic factor 4; Neurotrophic factor 5; Neurotrophin 4/5; Neurotrophin 5 (neurotrophin 4/5); Neurotrophin 5; Neurotrophin-4; Neurotrophin-5; Neurotrophin4; Neurotrophin4/5; Neurotrophin5;
分子量： 14/27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NT-4
交叉反应：Human, Mouse, Rat,
神经生长因子4/5抗体细胞定位：分泌型蛋白
产品介绍：background: Neurotrophin 4 (NT4; synonymous with NT5) belongs to the NGF beta family and is a survival factor for peripheral sensory sympathetic neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. NT4 levels are highest in the prostate, with lower levels in thymus, placenta, and skeletal muscle. NT4 is also expressed in embryonic and ***** tissues. Function: Target-derived survival factor for peripheral sensory sympathetic neurons. Subcellular Location: Secreted. Tissue Specificity: Highest levels in prostate, 神经生长因子4/5抗体lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and ***** tissues. DISEASE: Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. Similarity: Belongs to the NGF-beta family. Gene ID: 4909 Database links: Entrez Gene: 4909 Human Entrez Gene: 78405 Mouse Entrez 神经生长因子4/5抗体Gene: 25730 Rat Omim: 162662 Human SwissProt: P34130 Human SwissProt: Q80VU4 Mouse SwissProt: P34131 Rat Unigene: 266902 Human Unigene: 20344 Mouse Unigene: 44225 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Neurotrophic factor 4/5起源于同一基因家族， 故可称为NGF家族。神经生长因子4/5具有促进早期神经元的增殖与分化，维持成熟神经元的存活的生物学功能,能调控神经元再生的微环境、可促进运动神经元的存活和生长并能防止它受损及死亡。
神经生长因子4/5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid