胰岛素受体底物-3抗体
规格：1mg/1ml
英文名： IRS3
别名： IRS1--Insulin receptor substrate-3; IRS3; IRS-3; IRS3.
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse IRS-3
交叉反应：Mouse, Rat,
胰岛素受体底物-3抗体细胞定位：细胞浆 细胞膜
产品介绍：background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the 胰岛素受体底物-3抗体insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Gene ID: 16369 Database links: Entrez Gene: 16369 Mouse SwissProt: O54718 Mouse Important Note:胰岛素受体底物-3抗体 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胰岛素受体底物-3属于IRS家族。IRS作为insulin/IGF 信号途径的核心介子对细胞的生长、发育及新陈代谢的调节起关键作用。
胰岛素受体底物-3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 激酶和磷酸酶 糖尿病 ***病 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid