细胞色素c氧化酶VIIA亚型2抗体
规格:1mg/1ml
英文名: COX7A2
别名: COX7A2; Cytochrome c oxidase polypeptide VIIa-liver/heart; mitochondrial precursor (Cytochrome c oxidase subunit VIIa-L) (VIIaL); CX7A2_HUMAN.
分子量: 6.7kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human COX7A2
交叉反应:Human, Mouse, Rat, Cow, Sheep,
细胞色素c氧化酶VIIA亚型2抗体细胞定位:细胞浆 细胞膜 线粒体
产品介绍:background: Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform)细胞色素c氧化酶VIIA亚型2抗体of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1(muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]. Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Subcellular Location: Mitochondrion inner membrane Similarity: Belongs to the cytochrome c oxidase VIIa family. Gene ID: 1347 Database 细胞色素c氧化酶VIIA亚型2抗体links: Entrez Gene: 1347 Human o Entrez Gene: 12866 Mouse o Entrez Gene: 29507 Rat o Omim: 123996 Human o SwissProt: P14406 Human o SwissProt: P48771 Mouse o SwissProt: P35171 Rat o Unigene: 70312 Human o Unigene: 152627 Mouse o Unigene: 1745 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞色素c氧化酶VIIA亚型2抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导 线粒体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid