C-肽抗体
规格：1mg/1ml
英文名： C Peptide
别名： proinsulin precursor; Hyperproinsulinemia; INS; Insulin Precursor; IRDN; Proinsulin; Propeptide; C-Peptide; INS_HUMAN.
分子量： 3 kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide of human C Peptide
交叉反应：Human,
C-肽抗体细胞定位：分泌型蛋白
产品介绍：background: C Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C Peptide are produced. C peptide is released into the blood stream in equal amounts to insulin. C-肽抗体A test of C peptide levels will show how much insulin the body is making. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Function: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Subunit: Heterodimer of a B chain and an A chain linked by two disulfide bonds. Subcellular Location: Secreted. Similarity: Belongs to the insulin family. Gene ID: 3630 Database links: Entrez Gene: 3630 Human Omim: 176730 HumanC-肽抗体 SwissProt: P01308 Human Unigene: 272259 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. C肽是胰岛β细胞的分泌产物，与大、小鼠有部分交叉，它与胰岛素有一个共同的前体——胰岛素原 C肽是连接肽，因为*初它是连接A、B两条链的中间段，胰岛素原分解后才能独立存在，它也能从细胞释放到血液中。因此，从胰岛细胞分泌入血的主要成分有两种，一种是人们所熟悉的胰岛素，另一种就是C肽。 近年来，随着深入的研究，发现C肽是具有生物学活性的。并且，这种生物学活性对于延缓糖尿病慢性并发症的发生和发展可能具有重要的作用.
C-肽抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 信号转导 生长因子和** 糖尿病 细胞因子 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid