神经束蛋白抗体
规格：1mg/1ml
英文名： Neurofascin
别名： KIAA0756; Neurofascin; Neurofascin homolog; NF; Nfasc; Nfasc protein; NFASC_HUMAN; NRCAML; neurofascin 155 kDa isoform; Neurofascin155.
分子量： 132/150kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Neurofas
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse,
神经束蛋白抗体细胞定位：细胞膜
产品介绍：background: Neurofascin is a cell adhesion molecule involved in mediating axon recognition but also signaling axonal contact. Immunoglobulin domain cell adhesion molecule (cam) subfamily; members are components of neural cell adhesion molecules (N-CAM L1), Fasciclin II and the insect immune protein Hemolin. The subfamily also includes receptor domains such as as the extracelluar ligand binding domain of Fibroblast Growth Factor Receptor 2. Members are phylogenetically diverse, occuring throughout metazoa, and are not components of the adaptive immune system molecules found in jawed vertebrates. A predominant feature of most Ig domains is a disulfide bridge connecting 2神经束蛋白抗体 beta-sheets with a Trp packing against the disulfide bond. Function: Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions. Subunit: Horseshoe-shaped homodimer. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Similarity: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. 神经束蛋白抗体Gene ID: 23114 Database links: Entrez Gene: 23114 Human Entrez Gene: 269116 Mouse Entrez Gene: 116690 Rat Omim: 609145 Human SwissProt: O94856 Human SwissProt: Q810U3 Mouse SwissProt: P97685 Rat Unigene: 13349 Human Unigene: 326702 Mouse Unigene: 3048 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 神经生物学相关蛋白（Neurobiology）
神经束蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid