腺苷酸激酶-1抗体
规格：1mg/1ml
英文名： Adenylate Kinase 1
别名： Adenylate kinase isoenzyme 1; Adenylate kinase soluble; AK 1; AK1; AK-1; ATP AMP transphosphorylase; Myokinase; KAD1_HUMAN; ATP-AMP transphosphorylase 1.
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Adenylat
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Goat, Monkey,
腺苷酸激酶-1抗体细胞定位：细胞浆
产品介绍：background: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008]. 腺苷酸激酶-1抗体Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Subunit: Monomer. Subcellular Location: Cytoplasm. DISEASE: Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD) [MIM:612631]. Similarity: Belongs to the adenylate kinase family. Gene ID: 203 Database links: Entrez Gene: 203 Human Entrez Gene: 11636 Mouse Entrez Gene: 24183 Rat Omim: 103000 Human 腺苷酸激酶-1抗体SwissProt: P00568 Human SwissProt: Q9R0Y5 Mouse SwissProt: P39069 Rat Unigene: 175473 Human Unigene: 29189 Mouse Unigene: 79537 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. AK1存在于人类红细胞上及某些组织中的具有遗传多态性的同工酶, 腺苷酸激酶催化 ATP，AMP 和 ADP 的转化，它是维持各种腺苷酸平衡的关键酶。因此，腺苷酸激酶就成为调控腺苷酸库大小的靶标分子。
腺苷酸激酶-1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid