外周髓磷脂P0蛋白/P0蛋白抗体
规格:1mg/1ml
英文名: Myelin Protein Zero
别名: peripheral myelin prothein Zero; MPZ; MPP; Myelin P0 protein; CHM; CMT1; CMT1B; DSS; MYELIN GLYCOPROTEIN P-ZERO; MYELIN PROTEIN PERIPHERAL; Myelin protein zero; P0; MYP0_HUMAN.
分子量: 24kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human P0 prote
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Guinea Pig, Bovine,
外周髓磷脂P0蛋白/P0蛋白抗体细胞定位:细胞膜
产品介绍:background: Myelin protein-zero is the major structural protein of peripheral myelin, accounting for more than 50% of the protein present in the sheath of peripheral nerves. Expression of the gene encoding Myelin protein-zero (MPZ) is restricted to Schwann cells; MPZ is not found in the CNS. An integral membrane glycoprotein of ~28kDa, Myelin protein-zero is thought to link adjacent lamellae and thereby stabilize the myelin assembly. The other 3 major components of myelin are myelin basic protein, myelin proteolipid protein and myelin-associated glycoprotein.外周髓磷脂P0蛋白/P0蛋白抗体 Subunit: Homodimer and homotetramer. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Found only in peripheral nervous system Schwann cells. Similarity: Belongs to the myelin P0 protein family. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 4359 Database links: Entrez Gene: 4359 Human Entrez Gene: 17528 Mouse Omim: 159440 Human 外周髓磷脂P0蛋白/P0蛋白抗体SwissProt: P25189 Human SwissProt: P27573 Mouse Unigene: 591486 Human Unigene: 93883 Human Unigene: 9986 Mouse UniProtKB/Swiss-Prot: P25189.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 成熟的周围神经系统髓鞘主要的蛋白为P0蛋白,分子量28KDa,它具有单个跨膜区,是IgG超家族的成员之一。
外周髓磷脂P0蛋白/P0蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid