胸腺基质**细胞生成素-1抗体
规格：1mg/1ml
英文名： TSLP
别名： Thymic stromal lymphopoietin isoform 1; Thymic stromal lymphopoietin; Thymic stromal lymphopoietin protein TSLP; TSLP protein; TSLP_HUMAN.
分子量： 15kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TSP-1
交叉反应：Human,
胸腺基质**细胞生成素-1抗体细胞定位：
产品介绍：background: Thymic stromal lymphopoietin (TSLP) is a novel cytokine that was found to promote the development of murine B cells in vitro. This protein, which is expressed in a number of tissues including heart, liver and prostate, prevented apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ-3. Anti-interleukin (IL)-7 receptor antibodies (Abs) neutralized this effect indicating that TSLP binds to at least part of the IL-7 receptor complex. TSLP induced phosphorylation of signal transducer and activator of transcription (STAT)-5.胸腺基质**细胞生成素-1抗体 Function: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Subunit: Interacts with a receptor composed of CRLF2 and IL7R. Subcellular Location: Secreted. Tissue Specificity: Expressed in a number of tissues including heart, liver and prostate. Database links: Entrez Gene: 85480 Human Entrez Gene: 53603 Mouse Entrez Gene: 688621 Rat Omim: 607003 Human SwissProt: Q969D9 Human胸腺基质**细胞生成素-1抗体 SwissProt: Q9JIE6 Mouse Unigene: 389874 Human Unigene: 143716 Mouse Unigene: 201724 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胸腺基质**细胞生成素-1（胸腺基质细胞分泌的**细胞生成素-1） 为一种新型促进生长的细胞因子——胸腺基质**蛋白（TSLP）可以引发炎症反应， 这种炎症反应可以引起很多过敏性**和**。 TSLP可能是过敏性***重要的引发剂，已得到科学家的重视，如果证实了 TSLP是一种起始因子，抑制TSLP可以有效地****和其它过敏性**。
胸腺基质**细胞生成素-1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid