***敏感脂肪酶抗体
规格：1mg/1ml
英文名： HSL/LIPE
别名： Hormone sensitive lipase; hormone-sensitive lipase; Hormone sensitive lipase testicular isoform; HSL; LHS; Lipase hormone sensitive; LIPE; Hormone-sensitive lipase; LIPS_HUMAN.
分子量： 116kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from rat HSL N-term
交叉反应：Rat, Fruit Fly,
***敏感脂肪酶抗体细胞定位：细胞浆 细胞膜
产品介绍：background: HSL ( hormone- sensitive lipase ) is an enzyme involved in hydrolysis of stored triglycerides and fatty acids; important for regulation of energy homeostasis. It has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. Function: In adipose ***敏感脂肪酶抗体tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. Subunit: Interacts with PTRF in the adipocyte cytoplasm. Subcellular Location: Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Similarity: Belongs to the 'GDXG' lipolytic enzyme family. Gene ID: 3991 Database links:***敏感脂肪酶抗体 Entrez Gene: 3991 Human Entrez Gene: 16890 Mouse Entrez Gene: 25330 Rat Omim: 151750 Human SwissProt: Q05469 Human SwissProt: Q6NSL7 Human SwissProt: P54310 Mouse SwissProt: P15304 Rat Unigene: 656980 Human Unigene: 158548 Mouse Unigene: 333679 Mouse Unigene: 10566 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. HSL又称：敏感性甘油三酯脂肪酶，在脂肪动员中，脂肪细胞内**敏感性甘油三酯脂肪酶（HSL）起决定性作用，它是脂肪分解的限速酶，称为**敏感性脂肪酶。 肾上腺素、去甲肾上腺素、胰高血糖素等激活HSL促进脂肪动员；胰岛素，前列腺素E及烟酸等抑制HSL，抑制脂肪的动员。
***敏感脂肪酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 **学 生长因子和** 糖尿病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid