黄体**释放**类似物抗体
规格：1mg/1ml
英文名： GNRH
别名： luteinizing hormone-releasing hormone-like; [D-Trp6]-LHRH Fragment, 1-6; LHRH.
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide ([D-Trp6]-LHRH Fragment, 1-
交叉反应：Human,
黄体**释放**类似物抗体细胞定位：分泌型蛋白
产品介绍：background: The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012]. Function: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. S黄体**释放**类似物抗体ubcellular Location: Secreted. DISEASE: Hypogonadotropic hypogonadism 12 with or without anosmia (HH12) [MIM:614841]: A disorder characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. In some cases, it is associated with non-reproductive phenotypes, such as anosmia, cleft palate, and sensorineural hearing loss. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In the presence of anosmia, idiopathic hypogonadotropic hypogonadism is referred to as Kallmann syndrome, whereas in the presence of a normal sense of smell, it has been termed normosmic idiopathic hypogonadotropic hypogonadism 黄体**释放**类似物抗体(nIHH). Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the GnRH family. Database links: Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 生长因子和**（ Growth Factor and Hormones） ＬＨＲＨ拮抗剂可以竞争性结合垂体ＬＨＲＨ的受体，而使天然的ＬＨＲＨ不能发挥作用，进而抑制垂体的促性腺**的分泌，起到**性去垂体的作用，睾丸失去了促性腺**的刺激作用，分泌雄**和产生精子的功能随之受到抑制，实验证明ＬＨＲＨ拮抗剂同样是一种有前途的抗精子生成**。 应用ＬＨＲＨ抗体可用来研究痴呆和神经变性**、不孕不育、某些肿瘤方面的研究。 ＬＨＲＨ类似物作为一种男性避孕药的优点是没有生殖系统以外作用，无毒副作用，而且抗生育作用是可逆的 促性腺**释放**抗体
黄体**释放**类似物抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 生长因子和** ***病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid