硒蛋白W抗体
规格：1mg/1ml
英文名： Selenoprotein W
别名： MGC105482; SelW; SEPW1; Selenoprotein W; SELW_RAT.
分子量： 9.5kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Selenopr
交叉反应：Human, Mouse, Rat, Sheep,
硒蛋白W抗体细胞定位：
产品介绍：background: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein has been shown to function as a glutathione-dependent antioxidant in vivo. It is highly expressed in proliferating myoblasts and suggested to be involved in muscle growth and differentiation by protecting the developing myoblasts from oxidative stress. [provided by RefSeq]. 硒蛋白W抗体Function: Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency. Subunit: Interacts with DPYSL2, PRDX1, YWHAB, YWHAG, HSP70 and HSP90. Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitously expressed with highest levels in skeletal muscle and heart, moderate levels in brain, spinal cord, thyroid, spleen, prostate, ovary, small intestine and colon, and lowest levels in liver and lymph node. Similarity: Belongs to the SelWTH family. 硒蛋白W抗体SELW subfamily. Database links: UniProtKB/Swiss-Prot: P63301.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 硒蛋白-W（selenoprotein W）和一种存在于多种组织中的18ku硒蛋白P（18ku selenoprotein）。它们具有防止膜结构及生物大分子的氧化损伤；合成并调节DNA表达；促进精子生成、发育及维持其活力；保护内皮细胞和维护肌肉组织的正常功能等广泛的生理作用。该蛋白与人、羊有部分交叉。
硒蛋白W抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid