白介素2受体a链/IL-2RA抗体
规格：1mg/1ml
英文名： IL2RA/CD25
别名： Interleukin 2 receptor alpha chain; CD 25; CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL2 RA; IL-2RA; IL2R; IL2RA; IL2RAC; Interleukin 2 Receptor Alpha; Interleukin 2 receptor a
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse CD25
交叉反应：Human, Mouse, Rat,
白介素2受体a链/IL-2RA抗体细胞定位：细胞膜
产品介绍：background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown.白介素2受体a链/IL-2RA抗体 Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]. Function: Receptor for interleukin-2. Subunit: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Contains 2 Sushi (CCP/SCR) domains. Gene ID: 16184 Database links: Entrez Gene: 3559 Human Entrez Gene: 16184 Mouse SwissProt: P01589 Human SwissProt: P01590 Mouse Unigene: 231367白介素2受体a链/IL-2RA抗体 Human Unigene: 915 Mouse Omim: 147730 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD25抗原是分子量为55KD的单链糖蛋白，故又称白介素2受体。主要用于与**样肿瘤、自身**性**及同种异体移植排斥反应等**的研究。CD25是白介素受体的α亚单位，主要表达于活化的T细胞，在活化的B细胞、NK细胞和巨噬细胞也有一定量的表达。该抗体主要用于标记活化的**细胞。
白介素2受体a链/IL-2RA抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 细胞膜受体 细胞类型标志物 **细胞 t-**细胞 b-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid