前列腺素氧化环化酶1抗体
规格：1mg/1ml
英文名： Cyclooxygenase 1
别名： Cyclooxygenase-1; Cyclooxygenase 1; COX-1; COX 1; COX1; Cyclooxygenase1; Prostaglandin-endoperoxide synthase-1; prostaglandin-endoperoxide synthase 1; PTGS-1; Prostaglandin G/H synthase 1 precursor; p
分子量： 63kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Cyclooxy
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
前列腺素氧化环化酶1抗体细胞定位：细胞浆 细胞膜
产品介绍：background: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].前列腺素氧化环化酶1抗体 Function: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Subunit: Homodimer. Subcellular Location: Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Similarity: Belongs to the prostaglandin G/H synthase family. Contains 1 EGF-like domain. Gene ID: 5742 Database links: Entrez Gene: 5742 Human Entrez Gene: 19224 Mouse Entrez Gene: 24693 Rat Omim: 176805 Human SwissProt: P23219 Human SwissProt: P22437 前列腺素氧化环化酶1抗体Mouse SwissProt: Q63921 Rat Unigene: 201978 Human Unigene: 275434 Mouse Unigene: 44404 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 合成与降解（Synthesis and Degradation） COX1 前列腺素氧化环化酶-是前列腺素合成的关键酶之一，为诱导性酶，他参与细胞对生长因子、肿瘤促进因子和细胞因子的反应，这些因子均能诱导COX1表达，它也参与前列腺素的合成。
前列腺素氧化环化酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 **学 信号转导 合成与降解
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid