多能发育相关基因2抗体
规格：1mg/1ml
英文名： DPPA2
别名： Developmental Pluripotency Associated 2; developmental pluripotency associated gene2; PESCRG1; Pluripotent embryonic stem cell related protein 1; cancer/testis antigen 100; CT100; developmental plurip
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DPPA2 (2
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
多能发育相关基因2抗体产品介绍：background: SCRG1 (scrapie-responsive protein 1) is a 98 amino acid secreted protein that belongs to the SCRG1 family. The SCRG1 protein contains a 20-amino acid signal peptide, and is expressed abundantly in the central nervous system of human *****, but not at all in fetal brain. The protein is targeted to the Golgi apparatus and large dense-core vesicles/secretory granules in neurons. High levels of SCRG1 transcripts are also observed in testis and aorta. SCRG1 is associated with neurodegenerative changes observed in transmissible 多能发育相关基因2抗体spongiform encephalopathies. It may play a role in host response to prion-associated infections. The SCRG1 protein may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. The human and mouse SCRG1 proteins share 83% sequence identity. The SCRG1 gene is conserved in chimpanzee, cow, mouse, rat and chicken, and maps to human chromosome 4q34.1. Function: Dppa2 is a SAP domain protein expressed only in pluripotent cells and the developing germ line. Subcellular Location: Secreted. Tissue Specificity: Expressed 多能发育相关基因2抗体abundantly in the central nervous system of *****, but not at all in fetal brain. High levels of SCRG1 transcripts are also observed in testis and aorta. Similarity: Belongs to the SCRG1 family. Gene ID: 151871 Database links: Entrez Gene: 151871 Human Entrez Gene: 73703 Mouse Omim: 614445 Human SwissProt: Q7Z7J5 Human SwissProt: Q9CWH0 Mouse Unigene: 351113 Human Unigene: 27857 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多能发育相关基因2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 发育生物学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid