白介素2抗体
规格：1mg/1ml
英文名： IL2
别名： Interleukin-2; T-cell growth factor; Aldesleukin; IL 2; IL2; Interleukin 2; Interleukin2; Lymphokine; POIL2; T Cell Growth Factor; TCGF; IL2_HUMAN; IL2_MOUSE; Involved in regulation of T cell clonal e
分子量： 15kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IL-2 (21
交叉反应：Human,
白介素2抗体细胞定位：分泌型蛋白
产品介绍：background: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of 白介素2抗体this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells. Function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. Subcellular Location: Secreted. DISEASE: Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute白介素2抗体 lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. Similarity: Belongs to the IL-2 family. Gene ID: 3558 Database links: Entrez Gene: 3558 Human Entrez Gene: 16183 Mouse Entrez Gene: 116562 Rat Omim: 147680 Human SwissProt: P60568 Human SwissProt: P04351 Mouse SwissProt: P17108 Rat Unigene: 89679 Human Unigene: 14190 Mouse Unigene: 9871 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. IL-2作为一种T细胞生长因子在**应答及其调节中起重要作用,白介素-2的拮抗剂可用于同种移植排斥、T细胞性白血病以及某些自身**性**的**.胞内IL-2的水平是反映Th1 /Th2型细胞平衡状态的一个有用指标。
白介素2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 糖蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid