锌指脂蛋白抗体
规格：1mg/1ml
英文名： ZNF268
别名： zinc finger protein ZNF268; zinc finger protein 268 isoform c; zinc finger protein 3; zinc finger protein HZF3; HZF3; MGC126498; ZN268_HUMAN.
分子量： 108kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNF268
交叉反应：Human,
锌指脂蛋白抗体细胞定位：
产品介绍：background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. ZNF268 contains 24 锌指脂蛋白抗体C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in three to five week old embryos. ZNF268 has been implicated in human leukemia, due to the identification of an alternatively spliced form in leukemia patients. Two named isoforms of ZNF268 exist as a result of alternative splicing events. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus (Probable). Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 24 C2H2-type zinc fingers. 锌指脂蛋白抗体Contains 1 KRAB domain. Gene ID: 10795 Database links: Entrez Gene: 10795 Human Omim: 604753 Human SwissProt: Q14587 Human Unigene: 124047 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 锌指基因家族是人体中*大的基因家族，它参与细胞分化、胚胎发育，并与许多**的发生相关。 人类ZNF268基因是一个在人胚肝中特异性表达的C2H2型锌指基因，并可能在人的早期肝脏发育中起重要作用.
锌指脂蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：染色质和核信号 信号转导 转录调节因子 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid