脂多糖相关反应蛋白5/γ-taxilin抗体
规格：1mg/1ml
英文名： Gamma-taxilin
别名： chromosome X open reading frame 15; LSR5; CXorf15; Environmental lipopolysaccharide-responding gene protein; factor inhibiting activating transcription factor 4 (ATF4)-mediated transcription; Factor i
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Gamma-ta
交叉反应：Human, Mouse,
细胞定位：细胞核 细胞浆 细胞膜
脂多糖相关反应蛋白5/γ-taxilin抗体产品介绍：background: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]. Function: May be involved in intracellular vesicle脂多糖相关反应蛋白5/γ-taxilin抗体 traffic. Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression. Subunit: Binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A. Forms a heterodimer with ATF4 in osteoblasts. Subcellular Location: Nucleus membrane. Cytoplasm, cytosol. Tissue Specificity: Ubiquitously expressed. Expressed at high level in heart and skeletal muscle脂多糖相关反应蛋白5/γ-taxilin抗体. Expressed in brain, placenta, lung, liver, kidney and pancreas. Similarity: Belongs to the taxilin family. Database links: Entrez Gene: 353170 Mouse SwissProt: Q8BHN1 Mouse Unigene: 270186 Mouse Unigene: 371732 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脂多糖相关反应蛋白5/γ-taxilin抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 干细胞 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid