间隙连接蛋白45抗体
规格：1mg/1ml
英文名： Connexin-45
别名： Connexin 45; Connexin45; Connexin-45; CX 31.9; CX 45; CX31.9; CX45; DKFZp686P0738; Gap junction alpha 7 protein; Gap junction alpha-7 protein; Gap junction protein alpha 7 45kDa; Gap junction protein
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Connexin
交叉反应：Human, Mouse, Rat, Dog, Pig,
间隙连接蛋白45抗体细胞定位：细胞膜
产品介绍：background: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations 间隙连接蛋白45抗体in this gene have been associated with oculodentodigital dysplasia and heart malformations. Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. Subunit: A connexon is composed of a hexamer of connexins. Interacts with CNST. Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Similarity: Belongs to the connexin family. 间隙连接蛋白45抗体Gamma-type subfamily. Gene ID: 10052 Database links: Entrez Gene: 10052 Human Entrez Gene: 14615 Mouse Entrez Gene: 266706 Rat Omim: 608655 Human SwissProt: P36383 Human SwissProt: P28229 Mouse SwissProt: A4GVD1 Pig SwissProt: A4GG66 Rat Unigene: 195419 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 通道蛋白（Channel Protein） Connexin45又称缝隙连接膜通道蛋白alpha7，Cx45构成细胞间的通道,小分子成份可以借此在细胞间扩散。 Connexin-45是心肌缝隙连接蛋白的主要蛋白之一。
间隙连接蛋白45抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 信号转导 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid