神经纤毛蛋白2抗体
规格：1mg/1ml
英文名： Neuropilin 2
别名： NRP2; MGC126574; Neuropilin 2; Neuropilin-2; Neuropilin2; NP 2; NP2; NPN 2; NPN2; NRP 2; nrp2; PRO2714; Receptor for VEGF165 and semaphorins class3; Vascular endothelial growth factor 165 receptor 2;
分子量： 99kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NRP-2
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞膜
神经纤毛蛋白2抗体产品介绍：background: This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis.神经纤毛蛋白2抗体 Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Function: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. Subunit: Heterodimer with NRP1. Binds PLXNB1. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Belongs to the neuropilin family. Contains 2 CUB domains. Contains 2 F5/8 type C domains. Contains 1 MAM domain. Gene ID: 8828 Database links: Entrez Gene: 8828 Human Entrez Gene: 神经纤毛蛋白2抗体18187 Mouse Entrez Gene: 81527 Rat Entrez Gene: 374157 Chicken Entrez Gene: 541004 Cow Omim: 602070 Human SwissProt: O60462 Human SwissProt: O35375 Mouse SwissProt: O35276 Rat Unigene: 471200 Human Unigene: 266341 Mouse Unigene: 10816 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. NRP2是一种新发现的血管内皮生长因子共受体，前列腺癌和乳腺癌细胞系等肿瘤都表达NRP-1，NRP-2。它们与肿瘤生长和血管生成有关。
神经纤毛蛋白2抗体产品应用：IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid