纤维母细胞生长因子7抗体
规格：1mg/1ml
英文名： KGF
别名： FGF 7; FGF7; FGF-7; Fibroblast Growth Factor 7;HBGF 7; HBGF7; HBGF-7; Keratinocyte growth factor precursor; Heparin binding growth factor 7; Keratinocyte Growth Factor; FGF7_HUMAN; Heparin-binding gro
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from humna KGF
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Sheep,
纤维母细胞生长因子7抗体细胞定位：分泌型蛋白
产品介绍：background: KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in纤维母细胞生长因子7抗体 morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. Function: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Subunit: Interacts with FGFBP1. Interacts with FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Subcellular Location: Secreted. Tissue Specificity: Epithelial cell. Similarity: Belongs to the heparin-binding growth factors family. Gene ID:纤维母细胞生长因子7抗体 2252 Database links: Entrez Gene: 2252 Human Entrez Gene: 14178 Mouse Entrez Gene: 29348 Rat Omim: 148180 Human SwissProt: P21781 Human SwissProt: P36363 Mouse SwissProt: Q02195 Rat Unigene: 567268 Human Unigene: 330557 Mouse Unigene: 98842 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. KGF/FGF7 (Fibroblast growth factor 7) 又称：HBGF-7 纤维母细胞生长因子7，是FGF家族的主要成员之一。 FGF家族参与细胞生长、组织修复、胚胎生长发育、组织器官的形成、肿瘤的生长和侵润等诸多生理病理功能。 成纤维细胞生长因子7的促增生作用主要来源于角化上皮细胞而不是间质细胞和内皮细胞，因此人们又称之为：角化上皮细胞生长因子（KGF）。
纤维母细胞生长因子7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid