神经细胞粘附分子1抗体
规格：1mg/1ml
英文名： CD56
别名： CD56 antigen; Cell Adhesion Molecule Neural 1; MSK39; N CAM 120; N CAM 140; N CAM 180; NCAM 1; NCAM 120; NCAM 140; NCAM1; Neural cell adhesion molecule 1 120 kDa isoform; Neural cell adhesion molecule
分子量： 92kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD56/NCA
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞膜 分泌型蛋白
神经细胞粘附分子1抗体产品介绍：background: This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by神经细胞粘附分子1抗体 RefSeq, Jun 2011] Function: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Subcellular Location: Isoform 1, 2,: Cell membrane; Single-pass type I membrane protein. Isoform 3, 4: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 5, 6: Secreted. Similarity: Contains 2 fibronectin type-III domains. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. Gene ID: 4684 Database links: Entrez Gene: 4684 Human Entrez Gene: 17967 Mouse Entrez Gene: 24586 Rat Omim: 116930 Human SwissProt: P13591 Human SwissProt: P13595 Mouse SwissProt: P13596 Rat Unigene: 503878 Human Unigene: 711235 Human Unigene: 733031神经细胞粘附分子1抗体 Human Unigene: 439182 Mouse Unigene: 4974 Mouse Unigene: 11283 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 细胞粘附蛋白（Call Adhesion Protein） 神经元标志物 NCAM-1为神经细胞粘附分子，主要分布于神经组织，神经—肌肉接头，神经—***腺和某些***腺以及大多数神经外胚层来源的细胞、组织和肿瘤中。 NCAM 1主要用于视网膜母细胞瘤、髓母细胞瘤、星形细胞瘤、神经母细胞瘤等肿瘤方面的研究。CD56（神经细胞黏附分子，NCAM）表达于大部分神经外胚层来源的细胞系、组织和肿瘤如视网膜母细胞瘤、成神经管细胞瘤、星形细胞瘤以及成神经细胞瘤。它也表达于一些中胚层来源的肿瘤如横纹肌肉瘤。NK细胞以及NK细胞**瘤为阳性。CD56被认为是NK细胞肿瘤的重要标志物。该抗体识别分子量为180，145和125kDa亚型。
神经细胞粘附分子1抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 干细胞 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid