磷脂酸磷酸酶2C抗体
规格:1mg/1ml
英文名: PAP2c
别名: PPAP2C; EC 3.1.3.4; Phosphatidic acid phosphatase 2c; Lipid phosphate phosphohydrolase 2; LPP2; PAP 2c; PAP2 G; PAP2 gamma; Phosphatidic acid phosphatase 2c; Phosphatidic acid phosphatase type 2C; Pho
分子量: 33kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PAP2c
交叉反应:Human, Mouse, Rat, Pig, Cow,
细胞定位:
磷脂酸磷酸酶2C抗体产品介绍:background: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown 磷脂酸磷酸酶2C抗体to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. Function: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P. Subunit: Homodimer. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Found mainly in brain, pancreas and placenta.磷脂酸磷酸酶2C抗体 Similarity: Belongs to the PA-phosphatase related phosphoesterase family. Gene ID: 8612 Database links: Entrez Gene: 8612 Human Omim: 607126 Human SwissProt: O43688 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PAP2c-磷脂酸磷酸酶-2C 又称:PAP2-gamma、PAP2-G主要用于胰岛素、糖及脂肪代谢方面的研究。
磷脂酸磷酸酶2C抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 激酶和磷酸酶 脂蛋白 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid