白介素8抗体
规格:1mg/1ml
英文名: IL-8/CXCL8
别名: (Ala-IL-8)77; (Ser-IL-8)72; 3 10C; 310C; AMCF 1; AMCF1; b ENAP; Bbeta thromboglobulin like protein; Beta thromboglobulin like protein; C-X-C motif chemokine 8; CXC chemokine ligand 8; CXCL 8; CXCL8; E
分子量: 8/9kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human IL-8
交叉反应:Human, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:分泌型蛋白
白介素8抗体产品介绍:background: The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008] Function: IL-8 is a chemotactic factor that attracts neutrophils, basophils, 白介素8抗体and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. Subunit: Homodimer. Subcellular Location: Secreted. Post-translational modifications: Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form. Similarity:白介素8抗体 Belongs to the intercrine alpha (chemokine CxC) family. Gene ID: 3576 Database links: Entrez Gene: 3576 Human Entrez Gene: 396880 Pig Omim: 146930 Human SwissProt: P10145 Human SwissProt: P26894 Pig Unigene: 624 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 白介素-8
白介素8抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 生长因子和** 趋化因子 交换蛋白 细胞因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid