肠型脂肪酸结合蛋白抗体
规格:1mg/1ml
英文名: intestinal FABP
别名: FABP 2; FABP2; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein intestinal; Fatty acid-binding protein; I-FABP; IFABP; Intestinal fatty acid binding protein 2; MGC133132; FAB
分子量: 15kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from IFABP
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit,
肠型脂肪酸结合蛋白抗体细胞定位:
产品介绍:background: Intestinal FABP is an intestinal marker. It is expressed in the small intestine. Expression in the mucosal cells of the ileum extends from the midvillar region to the villus tips. It is thought to play a role in the intracellular transport of long chain fatty acids and their acyl CoA esters and may be involved in triglyceride rich lipoprotein synthesis. Function: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty肠型脂肪酸结合蛋白抗体 acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Gene ID: 2169 Database links: Entrez Gene: 2169 Human Entrez Gene: 14079 Mouse Entrez Gene: 25598 Rat Omim: 134640 Human SwissProt:肠型脂肪酸结合蛋白抗体 P12104 Human SwissProt: P55050 Mouse SwissProt: P02693 Rat Unigene: 282265 Human Unigene: 28398 Mouse Unigene: 91358 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Fabp2脂肪酸结合蛋白-2,参与脂肪酸代谢、运输、消化,该蛋白的异常增高使人的新陈代谢功能异常,影响人体消耗摄入的糖分,从而导致引发糖尿病的发生。FABP2多态性可能与2型糖尿病合并冠心病的胰岛素抵抗相关联。
肠型脂肪酸结合蛋白抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 **学 生长因子和** 糖尿病
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid