降钙素基因相关肽2抗体
规格：1mg/1ml
英文名： CGRP
别名： CGRP-I + CGRP-II; CGRP-1/2; Procalcitonin; Beta type CGRP; CALC2; CALCB; Calcitonin 1; Calcitonin 2; Calcitonin gene related peptide; Calcitonin gene related peptide II; Calcitonin related polypeptide
分子量： 3.8kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CGRP
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow,
细胞定位：分泌型蛋白
降钙素基因相关肽2抗体产品介绍：background: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]降钙素基因相关肽2抗体 Function: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. Subcellular Location: Secreted. Similarity: Belongs to the calcitonin family. Gene ID: 796 797 Database links: Entrez Gene: 796 Human Entrez Gene: 797 Human Entrez Gene: 116903 Mouse Entrez Gene: 12310 Mouse Entrez Gene: 171519 Rat Entrez Gene: 24241 Rat Omim: 114130 Human Omim: 114160 Human SwissProt: P01258 Human SwissProt: P06881 Human SwissProt: P10092 Human SwissProt: P70160 Mouse SwissProt: Q99JA0 Mouse SwissProt: P01256 Rat SwissProt: P01257 Rat Unigene: 37058 Human降钙素基因相关肽2抗体 Unigene: 534305 Human Unigene: 273838 Mouse Unigene: 4361 Mouse Unigene: 88080 Rat Unigene: 90085 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CGRP活性多肽，有37个氨基酸组成，具有多种生理功能，其药理作用已受到广泛重视. CGRP （又称CGRP-1/2或CGRPa/β）广泛分布于神经系统的一种神经肽，在外周及脊髓参与伤害性信息的传递及痛敏化的形成，并与P物质、兴奋性氨基酸、辣椒素1型受体、趋化因子、激活素、**素受体、**受体、神经生长因子、血管活性肠肽、5-羟色胺、糖皮质**等生物活性物质或受体在痛觉调制过程中存在相互影响。
降钙素基因相关肽2抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid