溶菌酶抗体
规格:1mg/1ml
英文名: Lysozyme
别名: 1 4 beta n acetylmuramidase c; 14 beta N acetylmuramidase; 14 beta N acetylmuramidase C; EC 3.2.1.17; lysosyme; Lysozyme C; Lysozyme C precursor; Lyz; LZM; Muramidase.
分子量: 17kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:Full length native Lysozyme
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Monkey, Cat,
细胞定位:分泌型蛋白
溶菌酶抗体产品介绍:background: Lysozyme catalyzes the hydrolysis of certain mucopolysaccharides of bacterial cell walls. Specifically, it catalyzes the hydrolysis of the bacterial cell wall beta glycosidic linkages between N acetylmuramic acid and N acetylglucosamine. It is found in spleen, lung, kidney, white blood cells, plasma, saliva, milk, and tears. Subcellular Location: Secreted. DISEASE: Defects in LYZ are a cause of amyloidosis type 8 (AMYL8) [MIM:105200]; also known as systemic non-neuropathic amyloidosis or Ostertag-type amyloidosis. AMYL8 is a hereditary 溶菌酶抗体generalized amyloidosis due to deposition of apolipoprotein A1, fibrinogen and lysozyme amyloids. Viscera are particularly affected. There is no involvement of the nervous system. Clinical features include renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash. Similarity: Belongs to the glycosyl hydrolase 22 family. Gene ID: 4069 Database links: Entrez Gene: 4069 Human Entrez Gene: 17105 Mouse Entrez Gene: 17110 Mouse Omim: 153450 Human SwissProt: P61626 Human SwissProt: P08905 Mouse 溶菌酶抗体Unigene: 524579 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 溶菌酶(lysozyme )又称细胞壁质酶(muramidase)或n-乙酰胞壁质聚糖水解酶(n-acetylmuramideglycanohydralase)。 对于哺乳动物溶菌酶,其牛、猪、猫、兔、猴、马、羊等动物的乳汁中分离出溶菌酶,其化学性质与人溶菌酶相似。 溶菌酶作为机体非特异**因子之一,参与机体多种**反应,在机体正常防御功能和非特异**中,具有保持机体生理平衡的重要作用。可改善和增强巨嗜细胞吞噬和消化功能,激活白细胞吞噬功能,并能改善细胞抑制剂所导致的白细胞减少,从而增强机体的抵抗力。
溶菌酶抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 激酶和磷酸酶 合成与降解
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid