小肠型脂肪酸结合蛋白抗体
规格：1mg/1ml
英文名： IFABP
别名： FABP 2; FABP2; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein intestinal; Fatty acid-binding protein; I-FABP; IFABP; Intestinal fatty acid binding protein 2; MGC133132; FAB
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IFABP
交叉反应：Human, Mouse, Rat,
细胞定位：
小肠型脂肪酸结合蛋白抗体产品介绍：background: The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and 小肠型脂肪酸结合蛋白抗体a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008] Function: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Subcellular Location: Cytoplasm.小肠型脂肪酸结合蛋白抗体 Tissue Specificity: Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Gene ID: 2169 Database links: Entrez Gene: 2169 Human Entrez Gene: 14079 Mouse Entrez Gene: 25598 Rat Omim: 134640 Human SwissProt: P12104 Human SwissProt: P55050 Mouse SwissProt: P02693 Rat Unigene: 282265 Human Unigene: 28398 Mouse Unigene: 91358 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 小肠脂肪酸结合蛋白(IFABP)主要是在小肠分泌的一种蛋白质,参与了脂肪酸的吸收和代谢。IFABP有可能通过干扰脂肪酸代谢而影响胰岛素敏感性。 IFABP主要用于2型糖尿病相关性的研究。
小肠型脂肪酸结合蛋白抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 生长因子和** 糖尿病 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid