麻疹病毒融合蛋白抗体
规格：1mg/1ml
英文名： Measles virus fusion protein
别名： Fusion glycoprotein F0; Fusion ; glycoprotein F2; Fusion glycoprotein; FUS_MEASE.
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Measles virus
交叉反应：Measles virus
细胞定位：
麻疹病毒融合蛋白抗体产品介绍：background: No data available. Function: Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.麻疹病毒融合蛋白抗体 This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity). Subunit: Homotrimer of disulfide-linked F1-F2 (By similarity). Tissue Specificity: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane 麻疹病毒融合蛋白抗体protein. Post-translational modifications: The inactive precursor F0 is glycosylated and proteolytically cleaved into F1 and F2 to be functionally active. The cleavage is mediated by cellular proteases during the transport and maturation of the polypeptide (By similarity). Similarity: Belongs to the paramyxoviruses fusion glycoprotein family. Database links: UniProtKB/Swiss-Prot: P69353.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
麻疹病毒融合蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**及病毒
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid