麻疹病毒血凝素抗体
规格:1mg/1ml
英文名: MV hemagglutinin glycoprotein
别名: H protein; HA; H; Measles virus hemagglutinin; Hemagglutinin glycoprotein; HEMA_MEASE.
分子量: 68kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from Measles virus
交叉反应:Measles virus
细胞定位:
麻疹病毒血凝素抗体产品介绍:Function: Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion. May use human CD46 and/or SLAMF1 as receptors for viral entry into the cell. The high degree of interaction between H and MCP/CD46 results麻疹病毒血凝素抗体 in down-regulation of the latter from the surface of infected cells, rendering them more sensitive to c3b-mediated complement lysis. Subunit: Interacts with human PVRL4; this interaction allows virus infection of the respiratory epithelium (By similarity). Interacts with human MCP/CD46 antigen and SLAMF1. Subcellular Location: Virion membrane; Single-pass type II membrane protein (Potential). Host cell membrane; 麻疹病毒血凝素抗体Single-pass type II membrane protein (By similarity). Similarity: Belongs to the paramyxoviruses hemagglutinin-neuraminidase family. Non-sialidase subfamily. Database links: UniProtKB/Swiss-Prot: P08362.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 麻疹病毒血凝素蛋白(Hemagglutinin protein,H)是介导麻疹病毒吸附、侵入宿主细胞的关键分子,麻疹病毒H蛋白在细胞膜上的表达,以及被麻疹病毒感染的细胞和未感染细胞的直接接触能够引起其受体CD46的表达下调.
麻疹病毒血凝素抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 **及病毒
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid