神经肽Y受体2抗体
规格：1mg/1ml
英文名： NPY2R
别名： Neuropeptide Y Receptor Type 2; Neuropeptide Y receptor Y2; NPY-Y2 receptor; NPY2R_HUMAN.
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NPY2R
交叉反应：Human, Mouse, Rat, Pig,
细胞定位：细胞膜
神经肽Y受体2抗体产品介绍：background: Neuropeptide Y (NPY), a peptide widely expressed in the brain, acts through the protein G-coupled receptors Y1, Y2 and Y5. This peptide modulates many important functions such as the control of energy balance and anxiety. Its involvement in brain development has been less investigated. Neuropeptide Y (NPY) receptors are members of a G protein coupled receptor superfamily and they mediate a variety of physiological responses including feeding and vasoconstriction. The endogenous ligands of NPY神经肽Y受体2抗体 receptors are a family of structurally related peptides, including NPY, peptide YY (PYY), and pancreatic polypeptide (PP). Increased activity of NPY and its receptors, Y1R, Y2R, and Y5R has been found in the brain in many forms of experimental obesity. Furthermore, several association studies have supported the association between NPY2R and obesity. Function: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. Subcellular Location: Cell membrane. Tissue Specificity: High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus.神经肽Y受体2抗体 Also detectable in caudate nucleus, hypothalamus and substantia nigra. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 4887 Database links: Entrez Gene: 4887 Human Entrez Gene: 18167 Mouse Entrez Gene: 66024 Rat Omim: 162642 Human SwissProt: P49146 Human SwissProt: P97295 Mouse Unigene: 37125 Human Unigene: 1433 Mouse Unigene: 64505 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经肽Y受体2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid