野生型P53诱导基因1抗体
规格：1mg/1ml
英文名： PAG608
别名： WIG-1; p53 activated gene 608; PAG608; FLJ12296; MGC10613; OTTHUMP; OTTHUMP; p53-activated gene 608 protein; PAG 608; WIG 1; Zinc finger matrin-type protein 3; Zinc finger protei
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PAG608 (
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse,
细胞定位：细胞核
野生型P53诱导基因1抗体产品介绍：background: This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. Function: Acts as a bona fide target gene of p53/TP53. 野生型P53诱导基因1抗体May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. Subunit: Interacts with dsRNA. Subcellular Location: Nucleus. Nucleus, nucleolus. Tissue Specificity: Highly expressed in ***** brain, and moderately in ***** kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal 野生型P53诱导基因1抗体gland, liver or small intestine. Similarity: Contains 3 matrin-type zinc fingers. Gene ID: 64393 Database links: Entrez Gene: 538512 Cow Entrez Gene: 64393 Human Entrez Gene: 22401 Mouse Entrez Gene: 64394 Rat Omim: 606452 Human SwissProt: Q0IIC4 Cow SwissProt: Q9HA38 Human SwissProt: O54836 Mouse SwissProt: O08781 Rat Unigene: 371609 Human Unigene: 35705 Mouse Unigene: 2925 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
野生型P53诱导基因1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid