促黄体生成素抗体
规格:1mg/1ml
英文名: LH beta
别名: luteinizing hormone beta; CGB 4; CGB4; hLHB; Interstitial cell stimulating hormone; Interstitial cell stimulating hormone beta chain; Leutropin; LH B; LHB; LSH B; LSH beta; LSHB; LH-B; LSH-B; LSH-beta
分子量: 13kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from midlle of huma
交叉反应:Human,
细胞定位:
促黄体生成素抗体产品介绍:background: Luteinizing Hormone is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Mutations in the Luteinizing Hormone (LHB) gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. Function: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Subunit: Heterodimer 促黄体生成素抗体of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. Subcellular Location: Secreted. Tissue Specificity: Pituitary gland. DISEASE: Hypogonadism LHB-related (HGON-LHB) [MIM:152780]: Characterized by infertility and pseudohermaphroditism. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the glycoprotein hormones subunit beta family. Gene ID: 3972 Database links: Entrez Gene: 3972 Human Omim: 152780 Human SwissProt: P01229 促黄体生成素抗体Human Unigene: 154704 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. LH和FSH都是垂体前叶产生的,由两条多肽链(即а和β亚单位)经非共价键结合的糖蛋白。LH和FSH都是呈脉冲式分泌,故有较明显的日内和日间变异。 女性月经中期的LH高峰促成排卵,男性LH主要刺激Legdig细胞产生睾丸酮,又协同FSH促进精子成熟。与FSH同时测定,是研究和判断下丘脑 — 垂体 — 性腺轴功能的常规检查方法。LH的测定在预测排卵时间上具有特殊重要意义,它还可用于绝经期检查,不孕症诊断和*****的监测等。
促黄体生成素抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:生长因子和** ***病
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid