胶质细胞谷氨酸运载蛋白1抗体
规格：1mg/1ml
英文名： EAAT1
别名： EA6; EAAT1; Excitatory amino acid transporter 1; FLJ25094; GLAST; GLAST1; Glial high affinity glutamate transporter; High affinity neuronal glutamate transporter; Slc1a3; Sodium dependent glutamate/as
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EAAT1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
胶质细胞谷氨酸运载蛋白1抗体产品介绍：background: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. [SUBCELLULAR LOCATION] Membrane; Multi-pass membrane protein. [TISSUE SPECIFICITY] Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia. [SIMILARITY] Belongs to the sodium: dicarboxylate (SDF) symporter(TC 2.A.23) family. Function: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly胶质细胞谷氨酸运载蛋白1抗体 removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Subunit: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A3 subfamily. Subcellular Location: Membrane. Tissue Specificity: Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia. Post-translational modifications: Glycosylated. DISEASE: Defects in SLC1A3 are the cause of episodic ataxia type 6 (EA6) [MIM:612656]. EA6 is characterized by episodic ataxia, seizures, migraine and alternating hemiplegia. Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A3 subfamily. Gene ID: 6507 Database links: Entrez Gene:胶质细胞谷氨酸运载蛋白1抗体 6507 Human Entrez Gene: 20512 Mouse Entrez Gene: 29483 Rat Omim: 600111 Human SwissProt: P43003 Human SwissProt: P56564 Mouse SwissProt: P24942 Rat Unigene: 481918 Human Unigene: 204834 Mouse Unigene: 34134 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. EAAT-1主要用于神经胶质细胞的损伤及退变方面的研究.
胶质细胞谷氨酸运载蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid