血型糖蛋白δ抗体
规格:1mg/1ml
英文名: GYPB
别名: CD235b; GLPB_HUMAN; Glycophorin-B; Glycophorin B; GlycophorinB; PAS-3; Sialoglycoprotein delta; SS-active sialoglycoprotein.
分子量: 8kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Glycopho
交叉反应:Human,
细胞定位:细胞膜
血型糖蛋白δ抗体产品介绍:background: Glycophorins A, B and C are sialoglycoproteins of the human erythrocyte membrane, which bear the antigenic determinants for the MN, Ss and Gerbich blood groups, respectively. Glycophorins span the membrane once and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. The human Glycophorin A gene maps to chromosome 4q31.21血型糖蛋白δ抗体, contains seven exons which are 97% homologous to Glycophorin B, and encodes a 150 amino acid protein. The human Glycophorin B gene maps to chromosome 4q31.21 and encodes a 91 amino acid protein. The human Glycophorin C gene maps to chromosome 2q14.3 and contains four exons. Glycophorin C transcript can generate two protein isoforms. Isoform 1 includes all 4 exons and encodes the full length 128 amino acid protein. Isoform 2 is missing exon 2 and encodes a 109 amino acid protein, which specifies the Yus subtype of the Gerbich phenotype. Function:血型糖蛋白δ抗体 This protein is a minor sialoglycoprotein in erythrocyte membranes. Subcellular Subcellular Location: Cell membrane; Single-pass type I membrane protein. Post-translational modifications: The N-terminal extracellular domain is heavily glycosylated on serine and threonine residues. Similarity: Belongs to the glycophorin-A family. Gene ID: 2994 Database links: Entrez Gene: 2994 Human Omim: 111740 Human SwissProt: P06028 Human Unigene: 654368 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血型糖蛋白δ抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid