干扰素诱导蛋白P78抗体
规格：1mg/1ml
英文名： MX1 + MX2
别名： IFI78; N-terminally processed; Human interferon regulated resistance GTP binding protein MXA; IFI 78; IFI 78K; IFI-78K; IFI78; IFI78K; Interferon induced GTP binding protein Mx1; Interferon induced pr
分子量： 73/79kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IFI78/MX
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆
干扰素诱导蛋白P78抗体产品介绍：background: The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-alpha/IFN-beta. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, 干扰素诱导蛋白P78抗体Mx1 is localized to the nucleus where, upon induction by IFN-alpha/IFN-beta, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family. Function: May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus. Subunit: Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7. Subcellular 干扰素诱导蛋白P78抗体Location: Cytoplasm. Similarity: Belongs to the dynamin family. Contains 1 GED domain. Gene ID: 4599 4600 Database links: Entrez Gene: 4599 Human Entrez Gene: 4600 Human Omim: 147150 Human Omim: 147890 Human Unigene: 517307 Human Unigene: 926 Human SwissProt: P20592 Human SwissProt: P20591 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
干扰素诱导蛋白P78抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid