白细胞介素31抗体
规格：1mg/1ml
英文名： IL-31
别名： Interleukin-31; 1700013B14RIK; IL31; interleukin-31 precursor; IL 31; IL-31; IL31_HUMAN; IL31_MOUSE; Interleukin 31.
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IL-31
交叉反应：Human,
细胞定位：分泌型蛋白
白细胞介素31抗体产品介绍：background: IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008] Function: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 白细胞介素31抗体heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. Subcellular Location: Secreted. Tissue Specificity: Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea. Gene ID: 386653 Database links: Entrez Gene: 386653 Human Entrez Gene: 76399 Mouse Omim: 609509 Human SwissProt: Q6EBC2 Human SwissProt: 白细胞介素31抗体Q6EAL8 Mouse Unigene: 569071 Human Unigene: 75049 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. IL-31是一种新型T细胞衍生的细胞因子,其功能受体复合物是由IL-31RA/GPL/GLM R和OSMR组成的异二聚体。它们在过敏性和非过敏性**中起重要作用。
白细胞介素31抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid