非酪氨酸蛋白激酶跨膜受体ROR1抗体
规格：1mg/1ml
英文名： ROR1
别名： dJ537F10.1; MGC99659; Neurotrophic tyrosine kinase; Neurotrophic tyrosine kinase receptor related 1; Neurotrophic tyrosine kinase, receptor related 1; NTRKR1; OTTHUMP; OTTHUMP; O
分子量： 100kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ROR1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞膜
非酪氨酸蛋白激酶跨膜受体ROR1抗体产品介绍：background: This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in ***** tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.非酪氨酸蛋白激酶跨膜受体ROR1抗体 [provided by RefSeq, Jun 2012] Function: Tyrosine-protein kinase receptor whose role is not yet clear. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and ***** CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. Contains 1 FZ (frizzled) domain. Contains 1 非酪氨酸蛋白激酶跨膜受体ROR1抗体Ig-like C2-type (immunoglobulin-like) domain. Contains 1 kringle domain. Contains 1 protein kinase domain. Gene ID: 4919 Database links: Entrez Gene: 4919 Human Entrez Gene: 26563 Mouse Entrez Gene: 362550 Rat Omim: 602336 Human SwissProt: Q01973 Human SwissProt: Q9Z139 Mouse Unigene: 654491 Human Unigene: 391716 Mouse Unigene: 57252 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
非酪氨酸蛋白激酶跨膜受体ROR1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：染色质和核信号 神经生物学 信号转导 激酶和磷酸酶 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid