离子转运相关蛋白SLC7A9抗体
规格:1mg/1ml
英文名: SLC7A9
别名: B(0+) type amino acid transporter 1; BAT1; CSNU3; Glycoprotein associated amino acid transporter b0+AT1; Solute carrier family 7 (cationic amino acid transporter y+ system) member 9; BAT1_HUMAN; B(0,+
分子量: 53kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC7A9
交叉反应:Human, Mouse, Rat, Dog, Pig, Rabbit,
细胞定位:细胞膜
离子转运相关蛋白SLC7A9抗体产品介绍:background: SLC7A9 belongs to the amino acid-polyamine-organocation (APC) superfamily. It is a disulfide linked heterodimer with the amino acid transport protein SLC3A1. SLC7A9 is involved in the high affinity, sodium independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high affinity 离子转运相关蛋白SLC7A9抗体reabsorption of cystine in the kidney tubule. Defects in SLC7A9 are a cause of non type I cystinuria (CSNU). CSNU arises from impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract. Three types of cystinuria have been described: type I (fully recessive or silent); type II (high excretor); type III (moderate excretor). Defects in SLC7A9 are associated with type II and type III cystinuria. They also might account for some non classic type I cystinuria cases. Function: Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule. Subunit: Disulfide-linked heterodimer with the amino acid transport protein SLC3A1. Subcellular Location:离子转运相关蛋白SLC7A9抗体 Membrane; Multi-pass membrane protein. Tissue Specificity: Kidney, small intestine, liver and placenta. Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Database links: UniProtKB/Swiss-Prot: P82251.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
离子转运相关蛋白SLC7A9抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 通道蛋白 交换蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid