胰辅脂酶抗体
规格：1mg/1ml
英文名： CLPS
别名： Colipase; Colipase pancreatic; Pancreatic colipase preproprotein.
分子量： 10kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CLPS
交叉反应：Human,
胰辅脂酶抗体细胞定位：分泌型蛋白
产品介绍：background: The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the胰辅脂酶抗体 destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] Function: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. Enterostatin has a biological activity as a satiety signal. Subunit: Forms a 1:1 stoichiometric胰辅脂酶抗体 complex with pancreatic lipase. Subcellular Location: Secreted. Tissue Specificity: Expressed by the pancreas. Similarity: Belongs to the colipase family. Gene ID: 1208 Database links: Entrez Gene: 1208 Human Omim: 120105 Human SwissProt: P04118 Human Unigene: 1340 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胰辅脂酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 ***病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid