细胞表面趋化因子受体1抗体
规格：1mg/1ml
英文名： CXCR1
别名： C C; C C CKR 1; CCCKR1; CD 181; CD128; CD181; CDw128a; Chemokine (C X C motif) receptor 1; Chemokine (C X C) receptor 1; Chemokine receptor 1; CKR 1; CMKAR1; CXCR 1; High affinity interleukin 8 recept
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CXCR1
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit,
细胞定位：细胞膜
细胞表面趋化因子受体1抗体产品介绍：background: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form 细胞表面趋化因子受体1抗体a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] Function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. Subcellular Location: Cell membrane. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 3577细胞表面趋化因子受体1抗体 Database links: Entrez Gene: 3577 Human Entrez Gene: 227288 Mouse Entrez Gene: 54258 Rat Omim: 146929 Human SwissProt: P25024 Human SwissProt: Q810W6 Mouse SwissProt: P70612 Rat Unigene: 194778 Human Unigene: 337035 Mouse Unigene: 138115 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CXCR1主要表达于浸润的炎性细胞和肠上皮细胞表面.
细胞表面趋化因子受体1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid