细胞角蛋白6抗体
规格:1mg/1ml
英文名: Cytokeratin 6
别名: KRT6A; CK6A; CK6B; CK6C; CK6D; CK 6E; K6A; CK6; K6C; K6D; KRT6C; Cytokeratin 6a; Cytokeratin 6B; Cytokeratin 6C; Cytokeratin 6D; Cytokeratin 6E; Cytokeratin6; Cytokeratin 6; k6a keratin; K6B; K6b kera
分子量: 60kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Cytokera
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
细胞角蛋白6抗体产品介绍:background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 细胞角蛋白6抗体gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]. Subunit: Heterodimer of a type I and a type II keratin. KRT6 isomers associate with KRT16 and/or KRT17. Interacts with TCHP. Tissue Specificity: Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath. Similarity: Belongs to the intermediate filament family. Gene ID:细胞角蛋白6抗体 286887 Database links: Entrez Gene: 286887 Human Entrez Gene: 3853 Human Entrez Gene: 3854 Human Entrez Gene: 16687 Mouse Entrez Gene: 16688 Mouse Omim: 148041 Human Omim: 148042 Human Omim: 612315 Human SwissProt: P02538 Human SwissProt: P04259 Human SwissProt: P48668 Human SwissProt: P50446 Mouse SwissProt: Q9Z331 Mouse Unigene: 700779 Human Unigene: 709234 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞角蛋白6抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid