磷酸化丝氨酸/苏氨酸蛋白激酶II β/casein kinase IIβ抗体
规格：1mg/1ml
英文名： phospho-CK II beta (Ser209)
别名： Casein Kinase 2 beta (phospho S209); p-Casein Kinase 2 beta (phospho S209); Casein Kinase 2 beta (p-S209); p-CSK2B(Ser209); phospho-CSK2B(Ser209); Casein kinase 2 beta polypeptide; casein kinase IIβ;
分子量： 24kDa
.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Pig, Cow,
细胞定位：
磷酸化丝氨酸/苏氨酸蛋白激酶II β/casein kinase IIβ抗体产品介绍：background: This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq, Jul 2008]. Function: Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic 磷酸化丝氨酸/苏氨酸蛋白激酶II β/casein kinase IIβ抗体activity of the alpha subunit. Subunit: Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. The beta subunit dimerization is mediated by zinc ions. Interacts with TCTEX1D3. Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation. Interacts with MUSK; mediates phosphorylation of MUSK by CK2. Post-translational modifications: Phosphorylated by alpha subunit. 磷酸化丝氨酸/苏氨酸蛋白激酶II β/casein kinase IIβ抗体Similarity: Belongs to the casein kinase 2 subunit beta family. Gene ID: 1460 Database links: Entrez Gene: 1460 Human Entrez Gene: 13001 Mouse Entrez Gene: 81650 Rat Omim: 115441 Human SwissProt: P67870 Human SwissProt: P67871 Mouse SwissProt: P67874 Rat Unigene: 73527 Human Unigene: 378901 Mouse Unigene: 137692 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化丝氨酸/苏氨酸蛋白激酶II β/casein kinase IIβ抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞周期蛋白 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid
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