组氨酸三聚体核苷结合蛋白1抗体
规格:1mg/1ml
英文名: HINT1
别名: histidine triad nucleotide binding protein 1; Adenosine 5' monophosphoramidase; Adenosine 5'-monophosphoramidase; HINT 1; HINT-1; histidine triad nucleotide binding protein 1; histidine triad nucleoti
分子量: 14kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HINT1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞核 细胞浆
组氨酸三聚体核苷结合蛋白1抗体产品介绍:background: The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]. 组氨酸三聚体核苷结合蛋白1抗体Function: Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2. Subunit: Homodimer. Interacts with CDK7. Subcellular Location: Cytoplasm. Nucleus. Note=Interaction with CDK7 leads to a more nuclear localization. Tissue Specificity: Widely expressed. Similarity: Belongs to the HINT family. Contains 1 HIT domain. Gene ID: 3094 Database links: Entrez Gene: 3094 Human Entrez Gene: 15254 Mouse Entrez Gene: 690660 Rat 组氨酸三聚体核苷结合蛋白1抗体Omim: 601314 Human SwissProt: P49773 Human SwissProt: P70349 Mouse SwissProt: P62959 Rat Unigene: 483305 Human Unigene: 425 Mouse Unigene: 138667 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组氨酸三聚体核苷结合蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 结合蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid