CD93抗体
规格：1mg/1ml
英文名： CD93
别名： C1qrp; Complement component C1q receptor; C1q/MBL/SPA receptor; C1qR(p); C1qr1; C1qRp; CD93 antigen; CD93 molecule; CDw93; Complement component 1 q subcomponent receptor 1; Complement component C1q re
分子量： 70kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD93
交叉反应：Human, Mouse, Rat, Dog,
细胞定位：细胞膜
CD93抗体产品介绍：background: The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008]. Function: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2)CD93抗体 and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. Subunit: Interacts with HCV core protein. Interacts with C1QBP; the association may represent a cell surface C1q receptor. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue SpecificityCD93抗体: Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin. Post-translational modifications: N- and O-glycosylated. Similarity: Contains 1 C-type lectin domain. Contains 5 EGF-like domains. Gene ID: 22918 Database links: Entrez Gene: 22918 Human Entrez Gene: 17064 Mouse Entrez Gene: 84398 Rat Omim: 120577 Human SwissProt: Q9NPY3 Human SwissProt: O89103 Mouse SwissProt: Q9ET61 Rat Unigene: 97199 Human Unigene: 681 Mouse Unigene: 162695 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD93抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 细胞粘附分子 细胞表面分子 糖蛋白 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid