促肾上腺皮质释放**受体1抗体
规格：1mg/1ml
英文名： CRHR1
别名： CRF1; Corticotropin releasing hormone receptor variant 1h;CRF-RI; CRF 1; CRF R; CRFR1; CRH R1h; CRF-R1; CRHR 1; CRHR; CRHR1f; Releasing hormone receptor 1; Seven transmembrane helix receptor; corticot
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CRHR1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
促肾上腺皮质释放**受体1抗体产品介绍：background: This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants one of which is a non-coding read-through transcript with the neighboring gene MGC57346. Function: Receptor for corticotropin releasing factor (CRH). Shows high-affinity CRF binding. The 促肾上腺皮质释放**受体1抗体activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subunit: Interacts (via N-terminal extracellular domain) with CRF and UCN. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe. Post-translational modifications: C-terminal Ser or Thr residues may be phosphorylated. Similarity: Belongs to the G-protein coupled receptor 2 family. Gene ID: 1394 Database links: Entrez Gene: 1394 Human Entrez Gene: 12921 Mouse Entrez Gene: 58959 Rat Omim: 122561 Human SwissProt: P34998 Human SwissProt: P35347 Mouse SwissProt: P35353 Rat Unigene:促肾上腺皮质释放**受体1抗体 417628 Human Unigene: 1892 Mouse Unigene: 10499 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
促肾上腺皮质释放**受体1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-200 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 生长因子和** ***病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid