转录因子Tbx3抗体
规格：1mg/1ml
英文名： TBX3
别名： T-box protein 3; T-box transcription factor TBX3; TBX3; TBX3-ISO; TBX3 ISO; UMS; XHL; Bladder cancer related protein XHL; T box 3; TBX3_HUMAN.
分子量： 82kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TBX3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核
转录因子Tbx3抗体产品介绍：background: Tbx3 gene is a member of a phylogenetically conserved family of genes that share a common DNA binding domain, the T box. T box genes encode transcription factors involved in the regulation of developmental processes. Tbx3 is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene转录因子Tbx3抗体 results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. Function: Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. Subcellular Location: Nucleus (Potential). Tissue Specificity: Widely expressed. DISEASE: Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands. 转录因子Tbx3抗体Similarity: Contains 1 T-box DNA-binding domain. Database links: Entrez Gene: 6926 Human Entrez Gene: 21386 Mouse Entrez Gene: 353305 Rat Omim: 601621 Human SwissProt: O15119 Human SwissProt: P70324 Mouse SwissProt: Q7TST9 Rat Unigene: 129895 Human Unigene: 219139 Mouse Unigene: 162144 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子Tbx3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid