DNA损伤自噬调整蛋白抗体
规格:1mg/1ml
英文名: DRAM
别名: Damage regulated autophagy modulator; Damage-regulated autophagy modulator; DNA damage-regulated autophagy modulator protein 1; dram1; DRAM1_HUMAN.
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DRAM
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,
DNA损伤自噬调整蛋白抗体细胞定位:细胞浆 细胞膜
产品介绍:background: This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008] Function: DNA损伤自噬调整蛋白抗体Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy. Subcellular Location: Lysosome membrane; Multi-pass membrane protein. Similarity: Belongs to the DRAM/TMEM150 family. Gene ID: 55332 Database links: Entrez Gene: 55332 Human Entrez Gene: 71712 Mouse Omim: 610776 Human SwissProt: DNA损伤自噬调整蛋白抗体Q8N682 Human SwissProt: Q9DC58 Mouse Unigene: 525634 Human Unigene: 35450 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA损伤自噬调整蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 心血管 **学 细胞凋亡
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid